Saima Machlovi

School: 
Hunter College
Graduation Status: 
Graduated

Description:

Graduate Student Researcher at Ichann School of Medicine at Mount Sinai. I received my Bachelor from Hunter College in Behavioral Neurobiology. I worked in Dr. Maria Pereira Figueiredo’s lab. I have always been passionate about science. Our project is on the role of heat shock protein on neurodegenerative diseases such as Alzhemier’s disease. Alzheimer’s disease is characterized by the formation of neurofibrillary tangles and senile plaques. These neurofibrillary tangles are formed due to the hyperphosphorylation of tau protein. Removal of these tau could be a relevant therapeutic strategy. In our study, we are using a compound called EC102, which is a compound that has been shown to act as an anti-tumor drug. We hypothesize that EC102 could also prevent the hyperphoshorylation of tau protein.  This summer, I will be at Brown University conducting research on memory and cognition. I plan to pursue a Ph.D program in Neuroscience after graduating from Hunter College. Hunter College’s Biopsychology and Behavioral Neuroscience program has inspired me significantly.

Presentation Summary:

  • Machlovi, S. (April, 2011) Neuronal induction of the heat shock protein 70 as a possible mechanism to overcome tau post-translational modification induced by Prostaglandin J2. Poster presented at Neuron Conference, NY
  • Machlovi, S. (April, 2011) Neuronal induction of the heat shock protein 70 as a possible mechanism to overcome tau post-translational modification induced by Prostaglandin J2. Poster presented at Science Day Conference, NY